First synthesis of double headed 1,2,4-triazino[5,6-b]indole acyclo C-nucleosides

Article abstract of DOI:10.1002/jccs.200500075

Heterocyclization of bis(2-oxo-indol-3-ylidene)-galactaric acid hydrazide (3) with a variety of one-nitrogen cyclizing agents gave the corresponding 1,4-bis{1,2,4-triazino[5,6-b]indol-3-yl}-galacto-tetritols 4-8. Acetylation of the latter double headed ac