Application of Enzymic Baeyer-Villiger Oxidations of 2-Substituted Cycloalkanones to the Total Synthesis of (R)-(+)-Lipoic Acid

DOI: 10.1039/c39950001563

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1563 - 1564 (1995)

Update date:2022-08-05

Topics:

Authors:

Adger, Brian

Bes, M. Teresa

Grogan, Gideon

McCague, Ray

Pedragosa-Moreau, Sandrine

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39950001563

Oxidation of ketones 1a-h using a monooxygenase from Pseudomonas putida NCIMB 10007 gave the lactones 2a-h in optically active form: lactone 2h was converted into (R)-(+)-lipoic acid 9.

Full text of DOI:10.1039/c39950001563

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:Octanoic acid, 6,8-dihydroxy-, methyl ester, (R)-

Cas No:88853-25-2

R&D Labs maybe for 88853-25-2

Hangzhou Donglou Bio-nutrient Co., Ltd.

Contact:+86-571-82225795,13967112289

Address:Louta Town, Xiaoshan,Hangzhou,Zhejiang
Wuhan Fortuna Chemical Co.,Ltd

website:http://www.fortunachem.com

Contact:86-27-59207850

Address:Add: Room 2015, No.2 Building, Kaixin Mansion No.107 Jinqiao Avenue, Wuhan, China
Shanghai Dano Pharmaceutical Co.,Ld.(expird)

Contact:+86-592-6266840

Address:Building 1 Room 512, 720 Cailun Rd, Zhangjiang High-Tech Park, Shanghai 201203, China
Daqing New Century Fine Chemical Co., Ltd.(expird)

Contact:010-57126694

Address:No.39, jinxing cun, honggang district
Liaoyang Xinyou Chemical Products Co.,Ltd.

Contact:+86-419-5165433 13604191870

Address:Huishang Road6-1, Hongwei District, Liaoyang, Liaoning, China

Relevant to this article

A Convenient and Simple Method for the α'-Chlorination of α,β and Conjugated Ketones

Doi:10.1021/jo00181a033
(1984)
Application of the goldilocks effect to the design of potent and selective inhibitors of phenylethanolamine N-methyltransferase: Balancing pK_a and steric effects in the optimization of 3-methyl-1,2,3,4- tetrahydroisoquinoline inhibitors by β-fluorination

Doi:10.1021/jm051262k
(2006)
Synthesis of 6-aryl-3,3-dimethyl-5-phenyl-2,3,5,6-tetrahydropyran-2,4- diones

Doi:10.1007/s11176-005-0445-1
(2005)
Highly diastereoselective asymmetric Mannich reactions of 1,3-dicarbonyls with acyl imines

Doi:10.1021/ol060304b
(2006)
A comprehensive study on infrared spectra of 2-hydroxyxanthone

Doi:10.1080/00387010.2011.607206
(2012)
Synthesis of 9α,11α-thiathromboxane A₂ methyl ester

Doi:10.1016/S0040-4039(00)88439-7
(1982)

Article Doi