Bioorganic and Medicinal Chemistry Letters p. 1931 - 1936 (1997)
Update date:2022-08-03
Topics:
Artico, Marino
Di Santo, Roberto
Costi, Roberta
Massa, Silvio
Scintu, Franca
Loi, Anna Giulia
De Montis, Antonella
La Colla, Paolo
Various 1-arylsulfonyl-3-(α-hydroxybenzyl)-1H-pyrroles were prepared by Friedel-Crafts reaction of 1-arylsulfonyl-1H-pyrroles with aroylchlorides in the presence of aluminum trichloride, followed by reduction of the ketones to the required carbinols. The compounds were identified as a novel class of non-nucleoside HIV-1 reverse transcriptase inhibitors characterized by the presence of a diarylcarbinol moiety, a chemical feature that strictly correlates with the anti-HIV-1 activity.
View MoreSuzhou Zhonghelong Chemical Tech Co., Ltd【License cancellation】
Contact:+86 571-12345678
Address:Dunhuang Road, Suzhou Industrial Park, No.128 building 701 room Mansion
Jiangsu Wanlong Chemical Co., Ltd.
website:http://www.wanlongchem.com
Contact:+86-511-86810993 0086-511-8681 0888;
Address:Quanzhou Town, Danyang City, Jiangsu
Huangshi Shennong Chemical Technology Co., Ltd
Contact:+86-714-3072290
Address:Eastern industrial park , Tieshan district , Huangshi city ,Hubei province , China
Contact:86-510-82853889
Address:Rm.3732, No.18-2,Yonghe Rd.,Wuxi,Jiangsu,214023,China
Huaian Double Win Chemicals Co.,Ltd.
Contact:+86-13511538872
Address:Blk 43,Greenland Century Town,Huaian District, Huaian City,Jiangsu Province,China
Doi:10.1039/b817274a
(2009)Doi:10.1016/j.mencom.2008.09.016
(2008)Doi:10.1021/jo00248a008
(1988)Doi:10.1016/S0040-4020(01)86911-8
(1987)Doi:10.1016/0022-328X(87)85125-2
(1987)Doi:10.1021/ja00221a030
(1988)
