The solid-state Michael addition of indole to 4-arylidene-3-methyl-5- pyrazolone

Article abstract of DOI:10.1002/jhet.5570360320

The Michael addition reactions of indole to 4-arylidene-3-methyl-1- phenyl-5-pyrazolone 1 were investigated in the solid state, by which a series of new compounds, 1-aryl-1-(3-indolyl)-1-(3'-methyl-1'-phenyl-5'-pyrazolon- 4'-yl)methanes 2, were easily obtained. This provides a feasible method of preparing novel compounds containing two heterocyclic groups at the same carbon.