FROM PENICILLIN TO PENEM AND CARBAPENEM. SYNTHESIS OF 2-OXOCARBAPENAM DERIVATIVE

DOI: 10.1016/S0040-4039(00)88148-4

Source and publish data:

Tetrahedron Letters p. 3251 - 3254 (1983)

Update date:2022-08-03

Topics:

Authors:

Hirai, Koichi

Iwano, Yuji

Fujimoto, Katsumi

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Article abstract of DOI:10.1016/S0040-4039(00)88148-4

Previously obtained 4-iodomethylazetidinone derivative (2a) is transformed via the trans-iodopropenylation method into the β-keto ester (8), which is thought to be an important precursor for the synthesis of the carbapenem derivatives.

Full text of DOI:10.1016/S0040-4039(00)88148-4

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