Journal of Medicinal Chemistry p. 100 - 103 (1986)
Update date:2022-08-05
Topics: TLC analysis Recrystallization Elution Epoxide Organic phase Aqueous phase Phenols Structure-activity relationships
Bouley, Etienne
Teulon, Jean-Marie
Cazes, Michele
Cloarec, Alix
Deghenghi, Romano
The synthesis of <<(thienylcarbonyl)amino>phenoxy>propanolamines and their β-adrenergic blocking and diuretic activity are described.Structure-activity relationships demonstrated that ortho substitution of the phenoxy ring with an hydrogen or an ester fun
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