cis-1,3,4,6,7,11b-Hexahydro-2-methyl-7-phenyl-2H-pyrazino[2,1-a] isoquinoline: a new atypical antidepressant.

DOI: 10.1021/jm00374a011

Source and publish data:

Journal of medicinal chemistry p. 995 - 1003 (1984)

Update date:2022-08-03

Topics:

Authors:

Griffith

Gentile Gentile

Robichaud

Frankenheim

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Article abstract of DOI:10.1021/jm00374a011

Molecular modelling studies suggested the synthesis of cis-1,3,4,6,7, 11b-hexahydro-2-methyl-7-phenyl-2H-pyrazino[2,1-a]isoquinoline (7a) as a rigid analogue of the atypical antidepressant mianserin. Acylation of 2,2-diphenylethylamine with chloroacetyl c

Full text of DOI:10.1021/jm00374a011

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