cis-1,3,4,6,7,11b-Hexahydro-2-methyl-7-phenyl-2H-pyrazino[2,1-a] isoquinoline: a new atypical antidepressant.

DOI: 10.1021/jm00374a011

Source and publish data:

Journal of medicinal chemistry p. 995 - 1003 (1984)

Update date:2022-08-03

Topics:

Authors:

Griffith

Gentile Gentile

Robichaud

Frankenheim

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00374a011

Molecular modelling studies suggested the synthesis of cis-1,3,4,6,7, 11b-hexahydro-2-methyl-7-phenyl-2H-pyrazino[2,1-a]isoquinoline (7a) as a rigid analogue of the atypical antidepressant mianserin. Acylation of 2,2-diphenylethylamine with chloroacetyl c

Full text of DOI:10.1021/jm00374a011

Products guided by the article

Product name:cis-1,3,4,6,7,11b-hexahydro-2-ethyl-7-phenyl-2H-pyrazino<2,1-a>isoquinoline-3,4-dione

Cas No:90083-51-5

R&D Labs maybe for 90083-51-5

QINGDAO TAOSIGN INTERNATIONAL TRADE CO.,LIMITED

Contact:+86-0532-82683616

Address:RM1402, Doublestar Seacoase 7#, No. 5 Guizhou Road, Qingdao, Shandong, China
Global United Biotechnology Inc.

Contact:+86-21-61618568

Address:Room 309, Building 6, NO.135, Jinyu Road, Pudong
KAIYUAN CHEMICAL COMPANY LIMITED.

website:http://www.kaiyuanchem.com

Contact:+86-22-59891255/66/77

Address:B-2205, Kuangshi International Building, Yingbin Road, XiangLuo Bay Business District, Binhai New area, Tianjin, China.
LIAONING DMSO CHEMICALS CO.,LTD.

website:http://www.chinadmso.com

Contact:+86-427-6503033

Address:FLOOR 16, BLOCK A, FINANCIAL SQUARE, XINGLONGTAI DISTRICT, PANJIN CITY, LIAONING P.R. CHINA
shijiazhuang baisheng chem co.; ltd

Contact:86-0311-80790826

Address:shijiazhuang hebei

Relevant to this article

Doi:10.1021/jo01256a071
(1969)
Optimizing ligand structure for low-loading and fast catalysis for alkynyl-alcohol and-amine cyclization

Doi:10.1039/c9dt01870k
(2019)
Discovery of a necroptosis inhibitor improving dopaminergic neuronal loss after mptp exposure in mice

Doi:10.3390/ijms22105289
(2021)
Intramolecular [4+2] cycloaddition reactions of pyridazino-[4,5-d]pyridazines with acetylenic side-chain dienophiles: Synthesis of f-annelated phthalazines

Doi:10.1002/jhet.5570310217
(1994)
An Amphiphilic Trinuclear Cobalt Cluster-containing Molecular Unit: Synthesis, Characterization and Langmuir-Blodgett Films

Doi:10.1039/DT9940001051
(1994)
Synthesis of tritiated N-[4-(2,4-diaminopteridine-6-methyl)-3,4-dihydro-2H-1,4- benzothiazine-7-carbonyl]-L-homo glutamic acid (MX-68)

Doi:10.1002/(SICI)1099-1344(199705)39:5<363::AID-JLCR982>3.0.CO;2-O
(1997)

Article Doi