
Journal of medicinal chemistry p. 995 - 1003 (1984)
Update date:2022-08-03
Topics:
Griffith
Gentile
Robichaud
Frankenheim
Molecular modelling studies suggested the synthesis of cis-1,3,4,6,7, 11b-hexahydro-2-methyl-7-phenyl-2H-pyrazino[2,1-a]isoquinoline (7a) as a rigid analogue of the atypical antidepressant mianserin. Acylation of 2,2-diphenylethylamine with chloroacetyl c
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