Synthesis of tritiated N-[4-(2,4-diaminopteridine-6-methyl)-3,4-dihydro-2H-1,4- benzothiazine-7-carbonyl]-L-homo glutamic acid (MX-68)

DOI: 10.1002/(SICI)1099-1344(199705)39:5<363::AID-JLCR982>3.0.CO;2-O

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 363 - 368 (1997)

Update date:2022-08-03

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Authors:

Matsuoka, Hiroharu

Kuroki, Toshio

Yano, Keiichi

Takeda, Yasuhisa

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Article abstract of DOI:10.1002/(SICI)1099-1344(199705)39:5<363::AID-JLCR982>3.0.CO;2-O

Synthesis of tritiated N-[4-(2,4-diaminopteridine-6-methyl)-3,4-dihydro-2H-1,4-benzothiazine-7 -carbonyl]-L-homoglutamic acid, [9-³H,]MX-68 (3), is described. [9-³H₁MX-68 (3) was prepared via tritiation at the carbonyl group in 2,4-bis(butanoylamino)-6-formylpteridine (7) with sodium borotritiide.

Full text of DOI:10.1002/(SICI)1099-1344(199705)39:5<363::AID-JLCR982>3.0.CO;2-O

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Product name:Hexanedioic acid,2-[[[4-[(2,4-diamino-6-pteridinyl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl]amino]-,(2S)-

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