Sinomenine derivatives with embedment of nitrogen-containing heterocycles exhibiting potent TNF-αinhibitory activity

DOI: 10.1007/s11426-012-4588-8

Source and publish data:

Science China Chemistry p. 2537 - 2547 (2012)

Update date:2022-08-02

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Authors:

Wang, Meng

Ma, Liyan

Lou, Yangtong

Bian, Chao

Zhou, Tingting

Zhou, Haibin

Liao, Hongze

Ma, Zhao

Yin, Dongsheng

Chen, Aizhong

Wang, Shaozhong

Yang, Zhenyu

Sun, Bing

Yao, Zhujun

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Article abstract of DOI:10.1007/s11426-012-4588-8

Inhibitory effect on tumor necrosis factor-α (TNF-α) production by sinomenine derivatives with embedment of small drug-like nitrogen hetereocyclic moieties has been studied in this work. Several new sinomenine derivatives having chlorophenyl substituent h

Full text of DOI:10.1007/s11426-012-4588-8

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