SYNTHESIS OF OLIGORIBONUCLEOTIDES BY USE OF S,S-DIPHENYL N-MONOMETHOXYTRITYL RIBONUCLEOSIDE 3'-PHOSPHORODITHIOATES

Article abstract of DOI:10.1016/0040-4020(84)85114-5

The fully protected ribonucleotide units (6a-d) have been synthesized in 42-62 percent overall yields by the 5- or 6-step reactions.The dimethoxtrityl, monomethoxytrityl, tetrahydropyran-2-yl, and phenylthio groups were introduced onto the 5'-OH, exo-amin