
Tetrahedron p. 733 - 736 (1984)
Update date:2022-08-05
Topics: Solvent Compound Production γ-Butyrolactone
Costisella, Burkard
Gross, Hans
Schick, Hans
Enamines of type 1 with anion-stabilizing substituents a are available by Horner-reaction of suitable phosphonates aldehydes.Deprotonation of 1 gives aminoallyl anions 2, which react with carbonyl compounds (depending on a) either to butyrolactones 8 resp. 10 or to 6-membered lactons 13.This process amounts to synthesis of lactones from two carbonyl compounds and an α-aminosubstituted phosphonate.
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