Design of a potent CB1 receptor antagonist series: Potential scaffold for peripherally-targeted agents

DOI: 10.1021/ml3000325

Source and publish data:

ACS Medicinal Chemistry Letters p. 397 - 401 (2012)

Update date:2022-07-29

Topics:

Authors:

Dow, Robert L.

Carpino, Philip A.

Gautreau, Denise

Hadcock, John R.

Iredale, Philip A.

Kelly-Sullivan, Dawn

Lizano, Jeffrey S.

O'Connor, Rebecca E.

Schneider, Steven R.

Scott, Dennis O.

Ward, Karen M.

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Article abstract of DOI:10.1021/ml3000325

Antagonism of cannabinoid-1 (CB₁) receptor signaling has been demonstrated to inhibit feeding behaviors in humans, but CB₁-mediated central nervous system (CNS) side effects have halted the marketing and further development of the le

Full text of DOI:10.1021/ml3000325

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