A NEW "ONE FLASK" PREPARATION OF 2-ALKYLAMINO-4-CHLOROQUINAZOLINES FROM ORTHO AMINOBENZONITRILES AND PHOSGENIMINIUM SALTS

DOI: 10.1016/S0040-4039(01)90009-7

Source and publish data:

Tetrahedron Letters p. 1557 - 1560 (1984)

Update date:2022-07-30

Topics:

Authors:

Kokel, Bruno

Menichi, Gabriel

Hubert-Habart, Michel

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Article abstract of DOI:10.1016/S0040-4039(01)90009-7

Phosgeniminium salts react easily with ortho amino-benzonitriles to give, selectively and quantitatively the corresponding 2-dialkylamino-4-chloroquinazolines.

Full text of DOI:10.1016/S0040-4039(01)90009-7

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