Total synthesis of granditropone, grandirubrine, imerubrine, and isoimerubrine

Article abstract of DOI:10.1021/ja00155a009

Concise total syntheses of the naturally occurring tropoloisoquinolines grandirubrine (1), imerubrine (2), and isoimerubrine (3) are detailed. The regioselective total synthesis of grandirubrine (1) is based on the [4 + 2]cycloaddition reaction of the α-p