Tetrahedron p. 73 - 78 (1984)
Update date:2022-08-05
Topics:
Marugg, J. E.
Tromp, M.
Jhurani, P.
Hoyng, C. F.
Marel, G. A. van der
Boom, J. H. van
The application of the phosphorylating agent 2-chlorophenyl-o,o-bis-<1-benzotriazolyl>-phosphate (HOBT-approach) for the introduction of 3'-5'-phosphotriester linkages between a properly 5'-protected (4,4'-dimethoxytrityl) deoxy-nucleoside and a deoxy-nucleoside having free OH groups is described.In this way, all sixteen partially-protected DNA dimers having a free 3'-OH group have been synthesized.The dimers thus obtained have been applied, using the HOBT-approach, to the synthesis of the DNA fragments d-CGCGCG, d-CGTACG and d-ATATTAATAAC.
View MoreYancheng KangdiSen Pharmaceutical Co., Ltd.
Contact:18951519681
Address:Yancheng City Funing County Yilin town Huaihai Road, No. 46
website:http://www.synchemie.com/
Contact:+86-574-87642758
Address:Room 901, Yinyi Bund Building， 132 Renmin Road
Contact:+1-284-4950244
Address:Box 3069, Road Town, Tortola, British Virgin Islands
Hangzhou ZeErRui Chemical Co., Ltd.
Contact:+86-571-82512721
Address:No 317,Jingling Road,Guali Town,Xiaoshan District
Tianjin Jiuri New Materials Co., Ltd.
Contact:+86-22-58889220
Address:C-5/6, Vison Hill, No.1 Gonghua Road, Huayuan Hi-tech Park, Tianjin, China.
Doi:10.1021/ol0623668
(2006)Doi:10.1016/S0040-4039(01)90106-6
(1984)Doi:10.1016/j.inoche.2006.01.021
(2006)Doi:10.1002/jlac.198319830611
(1983)Doi:10.1016/j.jorganchem.2006.08.022
(2006)Doi:10.1002/jhet.5570430530
(2006)
