SYNTHESIS OF AN 8-DEAZA ANALOG OF THE INTERMEDIATE IN THE THYMIDYLATE SYNTHETASE REACTION

DOI: 10.1016/S0040-4039(00)87125-7

Source and publish data:

Tetrahedron Letters p. 1431 - 1434 (1982)

Update date:2022-08-05

Topics:

Authors:

Srinivasan, Ananthachari

Broom, Arthur D.

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Article abstract of DOI:10.1016/S0040-4039(00)87125-7

Synthesis of an 8-deaza analog of the proposed intermediate in the thymidylate synthetase rection was accomplished from diethyl 8-deazafolic acid and an unambiguous proof of the structure is provided.

Full text of DOI:10.1016/S0040-4039(00)87125-7

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