Use of 1,1,1,3,3,3-Hexamethyldisilazane and N,O-Bis-(trimethylsilyl)acetamide in Aromatic Claisen Rearrangement: An Efficient Method for Preventing Abnormal Claisen Rearrangement

Article abstract of DOI:10.1016/S0040-4039(00)76781-5

Both 1,1,1,3,3,3-hexamethyldisilazane and N,O-bis-(trimethylsilyl)acetamide have been shown to suppress the formation of abnormal aromatic Claisen rearrangement products by efficiently trapping the incipient normal products as their silyl ethers under mil