Design, synthesis and binding at cloned muscarinic receptors of N-[5-(1'-substituted-acetoxymethyl)-3-oxadiazolyl] and N-[4-(1'-substituted-acetoxymethyl)-2-dioxolanyl] dialkyl amines

Article abstract of DOI:10.1016/S0968-0896(00)00092-4

Few muscarinic antagonists differentiate between the M₄ and M₂ muscarinic receptors. In a structure-activity study, aimed at discovering leads for the development of a M₄ muscarinic receptor-selective antagonist, we have s