Tetrahedron p. 2117 - 2122 (1984)
Update date:2022-07-30
Topics:
Laureillard, J.
Casadevall, E.
Solvolysis rates in methanol and 97percent hexafluoroisopropanol (HFIP) for four β-methyl and β-phenyl bicyclic tosylates, show that solvent nucleophilic assistance is operating in the former solvent.However, in 97percent HFIP, for three of the mentioned compounds, the mechanism involves ? or ? neighboring group assistance.The factors influencing the occurrence of these processes are discussed.Owing to these possible neighbouring group assistances in non-nucleophilic solvents used to obtain kc reference mechanisms, it is concluded that the ks/kc ratio which was proposed as a quantitative evaluation of solvent nucleophilic assistance must be used with caution.
View MoreShandong LuZhou Amino Acid Co., Ltd
Contact:86-539-2218025
Address:yishui economic and technical development zone zhenxing south road
NINGBO PANGS CHEM INT’L CO., LTD.
Contact:+86-0574-27666801
Address:Floor 21, Building 11, Xintiandi, No. 689, Shijiroad, Ningbo, Zhejiang, China
Guangzhou Chemical Reagent Factory
Contact:+86-20-8435 9820 or 8435 7345
Address:Southern Guangzhou, Guangdong, China
Zhejiang Genebest Pharmaceutical Co.,Ltd.
Contact:0086-571-63532866
Address:No.1 Jinboshi Rd Lishan Town Fuyang City Zhejiang Province China
Global United Biotechnology Inc.
Contact:+86-21-61618568
Address:Room 309, Building 6, NO.135, Jinyu Road, Pudong
Doi:10.1016/j.bmc.2008.12.011
(2009)Doi:10.1021/ol0624530
(2006)Doi:10.1039/c39820000745
(1982)Doi:10.1002/ejoc.200600863
(2007)Doi:10.1021/ic061359c
(2007)Doi:10.1246/cl.1984.1363
(1984)
