
Tetrahedron Letters p. 3175 - 3178 (1984)
Update date:2022-08-04
Topics:
Boger, Dale L.
Panek, James S.
A five-step approach to the preparation of the β-carboline CDE ring system of lavendamycin is detailed and is based on: (1) thermal cycloaddition of 3,5,6-tricarbomethoxy-1,2,4-triazine with the pyrrolidine enamine of o-bromopropiophenone followed by (2) implementation of a newly developed palladium (0) mediated β-carboline synthesis.
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