ISOLATION OF HYPOXOSIDE FROM HYPOXIS ROOPERI AND SYNTHESIS OF (E)-1,5-BIS(3',4'-DIMETHOXYPHENYL)PENT-4-EN-1-YNE

Article abstract of DOI:10.1016/S0031-9422(00)80449-5

Isolation of the known diglucoside of (E)-1,5-bis(3',4'-dihydroxyphenyl)pent-4-en-1-yne (hypoxoside) from Hypoxis rooperi is described.In vivo tests indicate low toxic properties.A general synthesis for the introduction of the pentenyne link between two aromatic rings is described.Key words: Hypoxis rooperi; Hypoxidaceae; corms; hypoxoside; 1,5-diphenylpent-4-en-1-yne; rooperol; synthesis.