Journal of the American Chemical Society p. 3524 - 3531 (2019)
Update date:2022-08-05
Topics:
Sijbesma, Eline
Hallenbeck, Kenneth K.
Leysen, Seppe
De Vink, Pim J.
Skóra, Lukasz
Jahnke, Wolfgang
Brunsveld, Luc
Arkin, Michelle R.
Ottmann, Christian
Modulation of protein-protein interactions (PPIs) by small molecules has emerged as a valuable approach in drug discovery. Compared to direct inhibition, PPI stabilization is vastly underexplored but has strong advantages, including the ability to gain se
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