α-Acylamino Radical Cyclizations: Syntheses of Isoretronecanol

DOI: 10.1021/ja00338a034

Source and publish data:

Journal of the American Chemical Society p. 8209 - 8217 (1984)

Update date:2022-08-05

Topics:

Authors:

Hart, David J.

Tsai, Yeun-Min

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja00338a034

α-Acylamino radicals 1-3 can be generated by tri-n-butyltin radical mediated cleavage of a carbon-sulfur bond.These radicals cyclize with good regio- and stereoselectivity to afford pyrrolizidinones.Cyclization products 12a and 23a were converted to the alkaloid isoretronecanol (4).

Full text of DOI:10.1021/ja00338a034

Products guided by the article

Product name:3-Buten-1-ol, 4-(phenylthio)-4-(trimethylsilyl)-, (E)-

Cas No:92845-38-0

R&D Labs maybe for 92845-38-0

Zhejiang Allied Chemical Co.,Ltd

Contact:18967038207

Address:Area A-30, High-tech Industrial Park, Quzhou, Zhejiang, China.
Shanghai united Scientific Co.,Ltd.

Contact:+86-21-53535353

Address:28F No.900 huaihai Road Shanghai China
Chengdu Aslee Biopharmaceuticals, Inc

Contact:18608018419

Address:Chengdu Aslee Biopharmaceuticals, Inc
Shaanxi Lighte Optoelectronics Material Co., Ltd.

Contact:+86-29-88320728-622/619/620

Address:No.55 INDUSTRY ROAD 2,XI'AN NATIONAL CIVIL AEROSPACE INDUSTRIAL PARK.XI'AN China 710065.
Suzhou Jingye Medicine & Chemical Co., Ltd

Contact:+86-512-66658588

Address:No. 88, Sanlian Street, Jinfeng Road, Suzhou New District, Jiangsu Province, P. R. China

Relevant to this article

Fluorination of 1,3-Dienes with Xenon Difluoride and (Difluoroiodo)Benzene

Doi:10.1021/jo00199a058
(1984)
Constructing a series of azide-bridged Cu^II magnetic low-dimensional coordination polymers by using pybox ligands

Doi:10.1002/ejic.201300107
(2013)
New 1,3-dioxolane and 1,3-dioxane derivatives as effective modulators to overcome multidrug resistance

Doi:10.1016/j.bmc.2007.01.024
(2007)
Asymmetric biomimetic oxidations of phenols using oxazolidines as chiral auxiliaries: The enantioselective synthesis of (+)- and (-)-dehydrodiconiferyl alcohol

Doi:10.1002/poc.1089
(2006)
Mild, efficient and highly stereoselective synthesis of (Z)-vinyl chalcogenides from vinyl bromides catalyzed by copper(I) in ionic liquids based on amino acids

Doi:10.1055/s-2006-958413
(2007)
Stereoselective total synthesis of achaetolide and reconfirmation of its absolute configuration

Doi:10.1016/j.tetlet.2010.09.070
(2010)

Article Doi