Utility of p-Nitrophenyl 3-Bromo-2,2-diethoxypropionate (NPBDP) in Heterocyclic Synthesis

DOI: 10.1021/jo00199a010

Source and publish data:

Journal of Organic Chemistry p. 4800 - 4805 (1984)

Update date:2022-08-04

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Authors:

LaMattina, John L.

Mularski, Christian J.

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Article abstract of DOI:10.1021/jo00199a010

p-Nitrophenyl 3-bromo-2,2-diethoxypropionate (NPBDP, 3) reacts with a variety of nucleophiles at the activated ester to afford the corresponding 3-bromo-2,2-diethoxypropionylated derivatives.With bifunctional nucleophiles, propionylation can be followed b

Full text of DOI:10.1021/jo00199a010

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