Chemical and Pharmaceutical Bulletin p. 332 - 334 (1998)
Update date:2022-08-04
Topics:
Koyama, Junko
Toyokuni, Izumi
Tagahara, Kiyoshi
The Diels-Alder reaction of 1,2,3-benzotriazine with several pyrrolidine enamines of carbonyl compounds was carried out in chloroform in the presence of zinc bromide to afford 2- or 3-mono-, or 2,3-disubstituted quinolines. This method was applied to the synthesis of the alkaloids, 2-propylquinoline and 2-pentylquinoline.
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