(TRIFLUOROMETHYL)KETENE SILYL ACETAL AS AN EQUIVALENT TO THE TRIFLUOROPROPIONIC ESTER ENOLATE: PREPARATION AND ALDOL-TYPE REACTIONS WITH ACETALS

Article abstract of DOI:10.1016/0040-4039(84)80047-7

The title reagent, readily prepared from methyl β,β,β-trifluoropropionate with trimethylsilyl triflate, is shown to react with a broad variety of acetals to provide the corresponding α-CF3 β-alkoxy esters in good yields.