Tetrahedron Letters p. 4421 - 4424 (1984)
Update date:2022-08-04
Topics:
Mori, Atsunori
Maruoka, Keiji
Yamamoto, Hisashi
A highly chemo- and stereoselective cleavage of acetals derived from (-)-(2R, 4R)-2,4-pentanediol with organotitanium reagents has been demonstrated.The reraction proceeds under mild condations in excellent yield and high chemoselectivity to give, after removel of auxiliary, the chiral alcohols of high enantiopurities.In addition, complexation of chiral acetals and TiCl4 followed by treatment with n-butyllithium also results in formation of the corresponding n-butylated alcohols with high stereoselectivity.
View MoreXiamen Huasing Chemicals Co.Ltd.
Contact:0086-592-6228397
Address:NO.24, Xinglin North 2nd Road,Jimei district
HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.
Contact:+86-186-02659358
Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China
Nanjing Spring & Autumn Biological Engineering Co., Ltd.
Contact:86-180510-83338
Address:Suite# 210, No. 1 BuildingNanjing Agricultural Biotechnology High-tech Entrepreneurship Center, No. 4 Tongwei Road, Xuanwu District, Nanjing,China
Shanghai Synmedia Chemical Co., Ltd
Contact:+86-21-38681880
Address:6th Floor, 11A Building, No.528 Ruiqing Road, Heqing town, Pudong new district, Shanghai China
Yueyang Hudex Pharmaceuticals Ltd.
Contact:0730-8748800
Address:Wujiang Bridge，Yueyang Economy & Technology Development Zone
Doi:10.1021/acs.jafc.6b04423
(2017)Doi:10.1016/S0040-4039(01)91090-1
(1984)Doi:10.1021/jo00202a014
(1985)Doi:10.1021/jm070090j
(2007)Doi:10.1016/S0040-4039(01)81381-2
(1984)Doi:10.1016/j.bmcl.2007.03.040
(2007)
