
Tetrahedron Letters p. 2977 - 2980 (1984)
Update date:2022-08-03
Topics:
Pfaltz, Andreas
Anwar, Saeed
Reduction of acyl cyanides with zinc in acetic acid in the presence of excess acetic anhydride leads to N-acetyl-α-aminoketones in good yields.An efficient three-step synthesis of 5-aminolevulinic acid by this method is described.
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(1984)