Total synthesis of halipeptin A, a potent anti-inflammatory cyclodepsipeptide from a marine sponge

DOI: 10.1016/j.tetlet.2005.12.026

Source and publish data:

Tetrahedron Letters p. 1081 - 1085 (2006)

Update date:2022-07-31

Topics: Total synthesis Starting Materials Anti-Inflammatory Natural product Cyclodepsipeptide Marine sponge

Authors:

Hara, Sousuke

Makino, Kazuishi

Hamada, Yasumasa

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Article abstract of DOI:10.1016/j.tetlet.2005.12.026

Total synthesis of halipeptin A, a potent anti-inflammatory cyclodepsipeptide, was achieved through proline-catalyzed asymmetric α-oxidation, diastereoselective aldol reaction, silver cyanide-mediated esterification, and macrolactamization.

Full text of DOI:10.1016/j.tetlet.2005.12.026

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