NEODIHYDROTHEBAINE AND BRACTAZONINE, TWO DIBENZAZONINE ALKALOIDS OF PAPAVER BRACTEATUM

Article abstract of DOI:10.1016/S0031-9422(00)82630-8

Two new dibenzazonine alkaloids, neodihydrothebaine and bractazonine were isolated from Papaver bracteatum.Their possible biosynthesis from thebaine is discussed.The structures of both new alkaloids are proven by synthesis.An isomeric dibenzazonine compound was also prepared. - Keywords: Papaver bracteatum; Papaveraceae; alkaloids; dibenzazonines; neodihydrothebaine; bractazonine; biosynthetic pathway; synthesis; 5,6,8,9-tetrahydro-2-methoxy-7-methyl-dibenzazonin-1,12-diol; 5,6,8,9-tetrahydro-2,10-dimethoxy-7-methyl-dibenzazonin-1-ol; 5,6,8,9-tetrahydro-2,11-dimethoxy-7-methyl-dibenz-azonin-1-ol; 5,6,8,9-tetrahydro-2,12-dimethoxy-7-methyl-dibenzazonin-1-ol.