SYNTHESIS OF UNNATURAL AMINO ACIDS: (S,S,S)-2-AZABICYCLOOCTANE-3-CARBOXYLIC ACID

DOI: 10.1016/S0040-4039(01)81471-4

Source and publish data:

Tetrahedron Letters p. 4479 - 4482 (1984)

Update date:2022-08-03

Topics:

Authors:

Teetz, V.

Geiger, R.

Gaul, H.

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Article abstract of DOI:10.1016/S0040-4039(01)81471-4

(S,S,S)-2-Azabicyclo<3.3.0>octane-3-carboxylic acid 1, a structural element of the very potent ACE inhibitor HOE 498, is readily available via a diastereo selective synthesis starting from serine or cystine.

Full text of DOI:10.1016/S0040-4039(01)81471-4

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