Tetrahedron Letters p. 4295 - 4298 (1984)
Update date:2022-08-05
Topics:
Kopecky, Jan
Smejkal, Jaroslav
Linhart, Igor
Hanus, Vladimir
Turecek, Frantisek
The title reaction yields (3R,5R) and (3R,5S) isomers of methyl 5-cyanotetrahydro-1,4-2H-thiazine-3-carboxylate, together with methyl 2-acetylthiazole-4-carboxylate as a minor by-product.The stereochemistry of the tetrahydrothiazine derivatives is discussed.
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(1984)
