One-pot synthesis of 2,3-dihydro-2-thioxoquinazolin-4(1H)-ones from nitro-compounds with the aid of tin(II) chloride

DOI: 10.1002/jhet.392

Source and publish data:

Journal of Heterocyclic Chemistry p. 939 - 943 (2010)

Update date:2022-08-04

Topics:

Authors:

Wang, Man-Man

Dou, Guo-Lan

Shi, Da-Qing

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Article abstract of DOI:10.1002/jhet.392

(Chemical Equation Presented) A facile synthetic method using SnCl ₂·2H₂O system to promote the novel reductive cyclization of 2-nitrobenzamides and isothiocyanates is described. Sequentially, a series of 2,3-dihydro-2-thioxoquinazolin-4(1H)-ones were synthesized in good yields.

Full text of DOI:10.1002/jhet.392

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