Journal of Organic Chemistry p. 470 - 473 (1985)
Update date:2022-08-04
Topics:
Hillis, Larry R.
Ronald, Robert C.
A total synthesis of the novel antibiotic (-)-grahamimycin A1 (1) is described.The macrocycle 1 was prepared from the convergence of 5(R)-hydroxy-2(E)-hexanoate 2 and (R)-7-octynoic acid 3, both of which were readiy attainable from (R)-methylox
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Doi:10.1248/cpb.58.1127
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