Inhibitors to Overcome Secondary Mutations in the Stem Cell Factor Receptor KIT

DOI: 10.1021/acs.jmedchem.7b00841

Source and publish data:

Journal of Medicinal Chemistry p. 8801 - 8815 (2017)

Update date:2022-08-15

Topics:

Authors:

Kaitsiotou, Helena

Keul, Marina

Hardick, Julia

Mühlenberg, Thomas

Ketzer, Julia

Ehrt, Christiane

Krüll, Jasmin

Medda, Federico

Koch, Oliver

Giordanetto, Fabrizio

Bauer, Sebastian

Rauh, Daniel

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Article abstract of DOI:10.1021/acs.jmedchem.7b00841

In modern cancer therapy, the use of small organic molecules against receptor tyrosine kinases (RTKs) has been shown to be a valuable strategy. The association of cancer cells with dysregulated signaling pathways linked to RTKs represents a key element in

Full text of DOI:10.1021/acs.jmedchem.7b00841

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