Highly Diastereofacial Selective Addition of Nucleophiles to 2-Alkyl-3-trimethylsilylalk-3-enyl Carbonyl Compounds. Stereoselective Preparation of β-Methylhomoallyl Alcohols and β-Hydroxy-α-methyl Ketones

DOI: 10.1039/c39840001130

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1130 - 1132 (1984)

Update date:2022-08-04

Topics:

Authors:

Sato, Fumie

Kusakabe, Masato

Kobayashi, Yuichi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39840001130

Nucleophiles react with 2-alkyl-3-trimethylsilylalk-3-enyl carbonyl compounds to afford 'Cram' products with high diastereoselectivity; this allows the stereoselective preparation of β-methylhomoallyl alcohols and β-hydroxy-α-methyl ketones.

Full text of DOI:10.1039/c39840001130

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:(1R,2R)-2-Methyl-1-phenyl-3-trimethylsilanyl-but-3-en-1-ol

Cas No:94393-62-1

R&D Labs maybe for 94393-62-1

Weifang Adde Economic And Trade Co.,LTD.

Contact:86-536-8885548

Address:Room 1402,Wanda Plaza B Block,No.958,Yuanfei Road,Kuiwen District
Wuhan Konberd Biotech Co., Ltd.

Contact:+86-27-87205925

Address:NO.666, Gaoxin Road, Eastlake High-tech zone
WUHU HUAHAI BIOLOGY ENGINEERING CO LTD

Contact:+86-553-3836920

Address:7/F NO.82 LAODONG ROAD WUHU CHINA
SJZ THLD IMP & EXP CO LTD

website:http://www.truewingroup.com

Contact:86-311-66699812

Address:NO.600 ZHONGSHAN EAST ROAD SHIJIAZHUANG
Hisyntech Corporation Limited

Contact:0086-22-23410962

Address:17-201, Ningfuli, Shuishanggongyuandong road,Nankai district, Tianjin, China

Relevant to this article

Studies on modified oligonucleotides

Doi:10.1080/10426500701734539
(2008)
A study on the racemization step in the synthesis of pyrrolidinols via cyclic α-hydroxyimides

Doi:10.1016/j.tetasy.2011.01.012
(2011)
Doi:10.1021/ja00866a024
(1962)
Experimental and computational study of the transformation of terminal alkynes to vinylidene ligands on trans-(chloro)bis(phosphine)Rh fragments and effects of phosphine substituents

Doi:10.1021/om700355r
(2007)
Chiral N-heterocyclic carbenes in natural product synthesis: Application of Ru-catalyzed asymmetric ring-opening/cross-metathesis and Cu-catalyzed allylic alkylation to total synthesis of baconipyrone C

Doi:10.1002/anie.200700501
(2007)
Self-association in {2-[3,4-alkylenedioxy-5-(3-pyridyl)]-thienyl}alkanols: An NMR, IR, and single-crystal X-ray study

Doi:10.1002/poc.1166
(2007)

Article Doi