Highly Diastereofacial Selective Addition of Nucleophiles to 2-Alkyl-3-trimethylsilylalk-3-enyl Carbonyl Compounds. Stereoselective Preparation of β-Methylhomoallyl Alcohols and β-Hydroxy-α-methyl Ketones

DOI: 10.1039/c39840001130

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1130 - 1132 (1984)

Update date:2022-08-04

Topics:

Authors:

Sato, Fumie

Kusakabe, Masato

Kobayashi, Yuichi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39840001130

Nucleophiles react with 2-alkyl-3-trimethylsilylalk-3-enyl carbonyl compounds to afford 'Cram' products with high diastereoselectivity; this allows the stereoselective preparation of β-methylhomoallyl alcohols and β-hydroxy-α-methyl ketones.

Full text of DOI:10.1039/c39840001130

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:(1R,2R)-2-Methyl-1-phenyl-3-trimethylsilanyl-but-3-en-1-ol

Cas No:94393-62-1

R&D Labs maybe for 94393-62-1

Hongyi Import & Export CO.,LTD

Contact:86-13319649499

Address:Nanzheng Neighborhood Commitees, Chongwen Office, Yongding District
Chinese Peptide Company

Contact:86-571-86737118-8689

Address:No.69, 12 Street, HEDA, Hangzhou, Zhejiang, China
Wuhan Konberd Biotech Co., Ltd.

Contact:+86-27-87205925

Address:NO.666, Gaoxin Road, Eastlake High-tech zone
Zibo Linzi Darong Fine Chemical Co., Ltd(expird)

Contact:86-532-67773200; 15689126900

Address:Qidu town,Linzi district,Zibo city,Shandong province,China
Qingdao XinYongAn Chemicals Co., Ltd

Contact:+86-532-81107967

Address:Chengyang dual-port industrial park by the sea，Qingdao

Relevant to this article

Studies on modified oligonucleotides

Doi:10.1080/10426500701734539
(2008)
A study on the racemization step in the synthesis of pyrrolidinols via cyclic α-hydroxyimides

Doi:10.1016/j.tetasy.2011.01.012
(2011)
Doi:10.1021/ja00866a024
(1962)
Experimental and computational study of the transformation of terminal alkynes to vinylidene ligands on trans-(chloro)bis(phosphine)Rh fragments and effects of phosphine substituents

Doi:10.1021/om700355r
(2007)
Chiral N-heterocyclic carbenes in natural product synthesis: Application of Ru-catalyzed asymmetric ring-opening/cross-metathesis and Cu-catalyzed allylic alkylation to total synthesis of baconipyrone C

Doi:10.1002/anie.200700501
(2007)
Self-association in {2-[3,4-alkylenedioxy-5-(3-pyridyl)]-thienyl}alkanols: An NMR, IR, and single-crystal X-ray study

Doi:10.1002/poc.1166
(2007)

Article Doi