An efficient optical resolution of nitrogen-centered chiral β-hydroxy-tetraalkylammonium salts via complexation with (R)-BINOL

Article abstract of DOI:10.1016/j.tetlet.2007.04.078

The optical resolution of nitrogen-centered chiral β-hydroxy-tetraalkylammonium bromides is demonstrated by using chiral BINOL as a complexing agent. Determination of the enantiopurities and absolute configurations of the resolved N-chiral tetraalkylammonium salts are described.