Conversions of up to 60% were achieved using ligand 1 with
2 mol% of Pd complex (entry 2), while for ligand 2 conver-
sions up to 56% were obtained with 0.2 mol% of Pd complex
(entry 5).
In conclusion, two new diaryl alkyl phosphine sulfonate ligands
have been synthesized as zwitterions. The structure of complex 1a
confirms the coordination of the phosphine sulfonate ligand in
a bidentate fashion. Both ligands 1 and 2 have been successfully
used in the palladium-catalysed Suzuki–Miyaura cross-coupling
reaction of aryl bromides as well as aryl chlorides in neat and
non-deareated water.
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Acknowledgements
10 Boronic Acids: Preparation and Applications in Organic Synthesis and
Medicine, ed. D. G. Hall, VCH, Weinheim, 2005.
We thank the Spanish Government (CTQ2004–04412/BQU,
Consolider Ingenio 2010, CSD2006–0003) and the Generalitat
de Catalunya (2005SGR007777 and Distinction for Research
Promotion, 2003 C.C.) for financial support. The Network of
Excellence IDECAT (contract NMP3-CT-2005–516972) is also
thanked for financial support to European integration. We thank
also the polymers group (Q.A.Q.O.) of the Universitat Rovira i
Virgili for the facilities to perform the microwave experiments.
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14 Microwave-assisted Suzuki–Miyaura coupling, for example: N. E.
Leadbeater, Chem. Commun., 2005, 2881.
This journal is
The Royal Society of Chemistry 2007
Dalton Trans., 2007, 2859–2861 | 2861
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