Stereoselective metabolism of conformational analogues of warfarin by β-naphthoflavone-inducible cytochrome P-450

DOI: 10.1021/jm00382a021

Source and publish data:

Journal of Medicinal Chemistry p. 503 - 506 (1985)

Update date:2022-07-30

Topics:

Authors:

Heimark Heimark

Trager Trager

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00382a021

Previous studies have shown that the structurally related oral anticoagulants warfarin and phenprocoumon are regioselectively hydroxylated in the 6- and 8-positions by hepatic microsomes obtained from 3-methylcholanthrene (3-MC) or β-naphthofalvone (BNF)

Full text of DOI:10.1021/jm00382a021

Products guided by the article

Product name:2',3',4',5',6'-pentadeuterio-7-hydroxycyclocoumarol

Cas No:94820-61-8

R&D Labs maybe for 94820-61-8

Jintan Jinnuo Chemical Co., Ltd.

Contact:+86-519-80199901

Address:Room 1804, Building 1, Huacheng Business Plaza, Jintan, Jiangsu, China
ShanDong XinDa Chemical CO.,LTD(expird)

Contact:086-0311-87580543

Address:No.168, High Technology Development Zone Jinan Shandong China
Huzhou City Linghu Xinwang Chemical Co.,Ltd.

Contact:86-572-3948695/3945236

Address:huzhou
Shandong LuZhou Amino Acid Co., Ltd

Contact:86-539-2218025

Address:yishui economic and technical development zone zhenxing south road
Huangshan Honghui Pharm Technology Co., Ltd.(expird)

website:http://www.honghuichem.com

Contact:18855958372

Address:Qingshan Wan No.1,Nanyuan Kou,SheXian Huangshan City,Anhui Province

Relevant to this article

NEW SYNTHETIC UTILITY OF SINGLET OXYGEN IN SULPHIDE PHOTO-OXIDATION. SELECTIVE AND STEREOSPECIFIC HYDROXYLATION α TO SULPHUR OF 4-SUBSTITUTED 3-BENZOYL-2,2-DIMETHYLTHIAZOLIDINES

Doi:10.1016/S0040-4020(01)96584-6
(1985)
The first stereoselective Pd-catalyzed addition of boronic acids onto aldehydes

Doi:10.1016/j.tetasy.2007.06.031
(2007)
Synthesis of 3-alkyl and arylapomorphines

Doi:10.1080/00397910701462773
(2007)
Reusable 1,2,4-triazolium based bronsted acidic room temperature ionic liquids as catalyst for mannich base reaction

Doi:10.1007/s10562-014-1312-7
(2014)
Benzimidazoles as potent and orally active mGlu5 receptor antagonists with an improved pk profile

Doi:10.1021/ml100215b
(2011)
Synthesis and characterization of palladium(II) complexes with chiral aminophosphine ligands: Catalytic behaviour in asymmetric hydrovinylation. Crystal structure of cis-[PdCl₂(PPh((R)-NHCHCH₃Ph)₂)₂]

Doi:10.1016/j.jorganchem.2007.02.020
(2007)

Article Doi