Journal of Organic Chemistry p. 1351 - 1355 (1985)
Update date:2022-07-29
Topics:
Katritzky, Alan R.
Saczewski, Franciszek
Marson, Charles M.
Alkylation of carbazole with <(chloromethyl)thio>benzene gave the key intermediate N-<(phenylthio)methyl>carbazole (2).Treatment of 2 with n-butyllithium at low temperature gave an α-lithio derivative 3, which reacted with a variety of electrophiles, affording N-<(phenylthio)alkyl>carbazoles 4a-g.Removal of the activating phenylthio group in 4a-g was achieved by Raney nickel desulfurization.Three successful routes to the novel N-(E)-styrylcarbazole (10) are described. 1H NMR and 13C NMR assignments of N-alkylcarbazoles are discussed.
View MoreContact:86-27-84888681
Address:Wuhan economic & technology development zone
Contact:+86-158-05817090
Address:ROOM 9F, FLAT 2, GUODU DEVELOPING BLDG, No.182, ZHAOHUI ROAD
website:http://www.chemdow.com
Contact:0086-10-82435335
Address:Room 401,Unit 3,4th Floor,Shangdijiayuan,Shangdi East Road, Haidian District,Beijing
Contact:+1 (647) 918 5848
Address:2343 BRIMLEY RD., Suite 250
Lonzeal Pharmaceuticals Co., Ltd.
website:http://www.lonzeal.com
Contact:+86-13381011962
Address:RM 801, Yue MOMA, No. 26 Anningzhuang Rd. Haidian District, Beijing, China
Doi:10.1007/s007060200088
(2002)Doi:10.1016/S0040-4039(01)81742-1
(1984)Doi:10.1021/ja990426h
(1999)Doi:10.1016/S0040-4020(01)99309-3
(1962)Doi:10.1021/ic701504z
(2007)Doi:10.1016/S0040-4039(00)95001-9
(1985)
