Spirocyclopropane compounds. IV. Synthesis of 5-acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-one-related compounds for evaluation as gastric antisecretory and antiulcer agents

DOI: 10.1248/cpb.32.3551

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 3551 - 3560 (1984)

Update date:2022-07-30

Topics:

Authors:

Watanabe

Kawada Kawada

Hirata Hirata

Maki Maki

Imada Imada

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.32.3551

5-Acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-one (1a) shows potent gastric antisecretory and antiulcer activities in rats. In an attempt to improve the pharmacological profile of 1a, we synthesized positional isomers, as well as the prenyloxy and oxim

Full text of DOI:10.1248/cpb.32.3551

NII-Electronic Library Service

Products guided by the article

Product name:Benzoic acid, 4-(phenylmethoxy)-2-[(tetrahydro-2-oxo-3-furanyl)oxy]-, methyl ester

Cas No:95449-68-6

R&D Labs maybe for 95449-68-6

Oren Hydrocarbons (Qingdao) Co., Ltd.

Contact:+86-532-68607667-801

Address:Room 3 # 302, No.9 Qingyun Road, Qingdao, China
Shijiazhuang Yunxuan Im&Export Co.,Ltd.

Contact:+86-311-83037514

Address:No.6 Hongbin Road
Liaoyang Xinyou Chemical Products Co.,Ltd.

Contact:+86-419-5165433 13604191870

Address:Huishang Road6-1, Hongwei District, Liaoyang, Liaoning, China
shanghai Tauto Biotech Co., Ltd

website:http://www.tautobiotech.com/en/index.htm

Contact:+86-21-51320588 ext. 8025

Address:No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA
HANGZHOU FOREWIN PHARMA CO., LTD

Contact:+86-571-89053961

Address:hangzhou

Relevant to this article

Optoelectronic property tailoring of conjugated heterocyclic azomethines - The effect of pyrrole, thiophene and furans

Doi:10.1002/poc.1894
(2012)
Effect of topology structure on the electrochemical behavior of hydrogen-bonded self-assembled Poly(4-vinylpyridine) -ferrocenyl dendron complexes

Doi:10.1016/j.jorganchem.2017.06.021
(2017)
Pentacyclic triterpenes. Part 5: Synthesis and SAR study of corosolic acid derivatives as inhibitors of glycogen phosphorylases

Doi:10.1016/j.bmcl.2007.08.057
(2007)
Novel estradiol-17α-1,2,4-triazoline derivatives. Synthesis and in vitro anabolic-catabolic properties and binding affinity to steroid receptors

Doi:10.1002/jhet.5570210539
(1984)
A Direct Synthesis of <(tert-Butoxycarbonyl)methylidene>azacycloalkanes from N-Alkyl Lactams

Doi:10.1021/jo00211a038
(1985)
EXTRACTION OF ORGANOMERCURY WITH 8-QUINOLINOL INTO BENZENE.

Doi:10.1246/bcsj.57.2271
(1984)

Article Doi