Journal of Organic Chemistry p. 85 - 88 (1988)
Update date:2022-07-31
Topics:
Howell, Henry G.
Brodfuehrer, Paul R.
Brundidge, Steven P.
Benigni, Daniel A.
Sapino, Chester
A general, total synthesis of (2'-fluoro-2'-deoxy-β-D-arabinofuranosyl)uracils 1a-d is described.A study of the coupling reaction beetwen 3,5-di-O-benzoyl-2-deoxy-2-fluoro-α-D-arabinofuranosyl bromide (7) and silylated pyrimidines 11a-d has resulted in a high overall yield for the five-step stereospecific synthesis of β-nucleosides.
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Doi:10.1021/ja01547a080
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(2008)Doi:10.1007/s10593-007-0213-8
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(1987)Doi:10.1039/a701932g
(1997)Doi:10.1021/jo00236a016
(1988)
