BIFUNCTIONAL CHIRAL SYNTHONS VIA BIOCHEMICAL METHODS. 4. CHIRAL PRECURSORS TO (+)-BIOTIN AND (-)-A-FACTOR.

DOI: 10.1016/S0040-4039(01)91101-3

Source and publish data:

Tetrahedron Letters p. 4999 - 5002 (1984)

Update date:2022-08-04

Topics:

Authors:

Wang, Yi-Fong

Sih, Charles J.

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Article abstract of DOI:10.1016/S0040-4039(01)91101-3

The chirons 3 and 4, derived from enzymic enantioselective hydrolysis of 1 and 2, are converted into the chiral lactones 5 and 6, key precursors to (+)-biotin and (-)-A-factor, respectively.

Full text of DOI:10.1016/S0040-4039(01)91101-3

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