TRANSFORMATION OF PROTOBERBERINES INTO BENZOPHENANTHRIDINES A NOVEL AND EFFICIENT SYNTHESIS OF ANTITUMOR BENZOPHENANTHRIDINE ALKALOIDS, FAGARONINE AND NITIDINE

DOI: 10.1016/S0040-4039(01)81554-9

Source and publish data:

Tetrahedron Letters p. 5169 - 5172 (1984)

Update date:2022-08-04

Topics:

Authors:

Hanaoka, Miyoji

Yamagishi, Hiroshi

Marutani, Mari

Mukai, Chisato

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Article abstract of DOI:10.1016/S0040-4039(01)81554-9

Antileukemic benzophenanthridine alkaloids, fagaronine (1a) and nitidine (1c) were synthesized from the corresponding protoberberines through C₆-N bond fission and subsequent cyclization between C₆ and C₁₃ position of the protoberberines.

Full text of DOI:10.1016/S0040-4039(01)81554-9

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