Benzodiazepine receptor binding and anticonflict activity in a series of 3,6-disubstituted pyridazino[4,3-c]isoquinolines devoid of anticonvulsant properties

DOI: 10.1021/jm00147a034

Source and publish data:

Journal of Medicinal Chemistry p. 1314 - 1319 (1985)

Update date:2022-08-02

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Authors:

Toja Toja

Tarzia Tarzia

Barone Barone

Luzzani Luzzani

Gallico Gallico

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Article abstract of DOI:10.1021/jm00147a034

A series of 3,6-disubstituted pyridazino [4,3-c]isoquinolines were synthesized and tested for their ability to inhibit the binding of [³H]diazepam to rat brain receptors in vitro. Compounds bearing a phenyl, 4-methyoxyphenyl, or methyl group at

Full text of DOI:10.1021/jm00147a034

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