Acylation of oxazoles by the copper-mediated reaction of oxazol-2-ylzinc chloride derivatives

DOI: 10.1016/0040-4039(95)02051-9

Source and publish data:

Tetrahedron Letters p. 9453 - 9456 (1995)

Update date:2022-08-02

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Authors:

Harn, Nancy K.

Gramer, Christine J.

Anderson, Benjamin A.

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Article abstract of DOI:10.1016/0040-4039(95)02051-9

C-2 acylation of oxazole derivatives is accomplished by reaction of oxazol-2-ylzinc chloride reagents with acid chlorides in the presence of cuprous iodide. O-acylated vinylisonitriles, which are the sole product from the corresponding reaction employing

Full text of DOI:10.1016/0040-4039(95)02051-9

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