Acylation of oxazoles by the copper-mediated reaction of oxazol-2-ylzinc chloride derivatives

Article abstract of DOI:10.1016/0040-4039(95)02051-9

C-2 acylation of oxazole derivatives is accomplished by reaction of oxazol-2-ylzinc chloride reagents with acid chlorides in the presence of cuprous iodide. O-acylated vinylisonitriles, which are the sole product from the corresponding reaction employing