NATURALLY-OCCURRING ACETYLENIC COMPOUNDS AND DERIVATIVES REGIO-AND STEREOCONTROLLED CHLOROFORMYLATION OF 2-(1-PROPYNYL)THIOPHENE AND 2-PHENYL-5-(1-PROPYNYL)THIOPHENE

Article abstract of DOI:10.1016/S0040-4020(01)96509-3

2-Phenyl-5-(1-propynyl)thiophene (1), isolated from Coreopsis grandiflora, and 2-(1-propynyl)thiophene (5), an immediate precursor in the synthesys of junipal (2), were synthesized in high yield by a Pd-catalyzed reaction between propyne and 2-iodo-5-phen