Tetrahedron Letters p. 933 - 936 (1985)
Update date:2022-08-05
Topics: Organic synthesis Experimental Phosphorylating agent S-4-METHYLPHENYL-O,O-BIS(1-BENZOTRIAZOLYL)PHOSPHOROTHIOATE Phosphorothioate
Wreesmann, C. T. J.
Fidder, A.
Veeneman, G. H.
van der Marel, G. A.
van Boom, J. H.
The phosphorylating agent obtained by treatment of S-4-methylphenyl phosphorodichloridothioate with 1-hydroxybenzotriazole can not only be applied for the introduction of polyphosphate functions at the terminal ends of nucleic acids, but also for the formation of 3'-5'-phosphotriester linkages.
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