Tetrahedron p. 4151 - 4158 (2016)
Update date:2022-07-30
Topics:
Rajbongshi, Kamal Krishna
Hazarika, Debojit
Phukan, Prodeep
A new approach has been developed for oxidative transformation of alkynes by controlled manipulation of TsNBr2mediated process. Alkynes could be readily converted to ketones and α-bromoketones via an oxybromination–debromination sequence. When alkynes are treated successively with TsNBr2, KI and Na2SO3in a mixture of acetone and water at room temperature, corresponding ketones were obtained. On the other hand, treatment of alkynes with TsNBr2and Na2SO3in a mixture of ethyl acetate, acetone and water at room temperature could produce corresponding α-bromoketones. 1-Bromoalkynes could also be synthesized from corresponding alkynes within a very short time using TsNBr2at room temperature. In all cases, excellent yields of corresponding products are obtained.
View Morewebsite:http://www.angchenchem.com
Contact:+86-510-88302099 82327577
Address:Rm. 404/405, Floor 4th, No. 983 FengXiang Road, Wuxi, China
Engineering Research Center of Pesticide, Heilongjiang Province
Contact:+86-451-86609001
Address:No.74 of Xuefu Road, Nangang District,
Suzhou Credit International Trading Co., Ltd
Contact:+86-512-65398039
Address:Qingdeng, Hightech. District, Suzhou
ZHUHAI HAIRUIDE BIOSCIENCE AND TECHNOLOGY CO.,LTD
website:http://www.zhhairuide.com
Contact:+8613326687259/+86-756-7789199
Address:No.10 Yonghui Road
website:http://www.sigmaaldrich.com
Contact:800 558-9160
Address:Industriestrasse 25CH-9471 Buchs SGSwitzerland
Doi:10.1016/S0040-4039(00)98425-9
(1985)Doi:10.1007/BF00948068
(1985)Doi:10.1016/S0040-4039(00)98647-7
(1985)Doi:10.1021/om00130a024
(1985)Doi:10.1002/jps.2600530517
(1964)Doi:10.1016/j.chembiol.2018.11.010
(2019)