A New Class of High Affinity Ligands for the Neurokinin A NK2 Receptor: ψ(CH2NR) Reduced Peptide Bond Analogues of Neurokinin A4-10

DOI: 10.1021/jm00099a024

Source and publish data:

Journal of Medicinal Chemistry p. 3949 - 3955 (1992)

Update date:2022-07-29

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Authors:

Harbeson, Scott L.

Shatzer, Scott A.

Le, Tieu-Binh

Buck, Stephen H.

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Article abstract of DOI:10.1021/jm00099a024

Analogues of 10>NKA_4-10 were synthesized in which each of the amide bonds was sequentially replaced with the reduced amide ψ(CH2NH) bond to determine the effect of this structural modification on the antagonism of NKA binding to

Full text of DOI:10.1021/jm00099a024

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